COcoa Supplement and

Multivitamin Outcomes Study

Who is eligible?


Women aged 65 years and older

 


    • Have not had a heart attack or stroke

    • Have not had cancer in the past 2 years (excluding skin cancer)


Men aged 60 years and older

 


    • Have not had a heart attack or stroke

    • Have not had cancer in the past 2 years (excluding skin cancer)



Participants are asked to:


1) Take 3 study pills every day for 4 years:

 


    • 2 cocoa extract or placebo capsules and 1 multivitamin or placebo tablet

    • The placebos look exactly like the cocoa extract or multivitamin, but contain none of the active ingredients



2) Avoid outside use of:

 


    • Cocoa extract supplements (You can still eat chocolate!)

    • Multivitamins, including eye vitamins like PreserVision, Ocuvite and AREDS



3) Limit daily supplement intake:

 


    • Vitamin D: 1000 IU/day maximum

    • Calcium: 1200 mg/day maximum



4) Complete health and diet questionnaires



5) Provide consent to obtain medical records related to new cases of heart disease, cancer, or other health outcomes



6) Join sub-studies that include possible compensation (optional)

 



All information that you provide will be held strictly confidential and used only for medical research purposes.

 

   COMPLETE THE FIRST QUESTIONNAIRE NOW

 

 

  RECEIVE THE FIRST QUESTIONNAIRE BY MAIL

 

 

 

 

 




































COSMOS Trial

Brigham and Women’s Hospital  | Division of Preventive Medicine | 900 Commonwealth Avenue  |  Boston, MA  02215  |  800-633-6913

COSMOStrial@partners.org